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Preoperative management of patients with thyroid dysfunction who are candidates for CABG

Preoperative management of patients with thyroid dysfunction who are candidates for CABG

Mozhgan Karimifar

MD
Isfahan University of Medical Sciences

15 NOVEMBER 2018

  • Thyroid disease is common; the prevalence is higher in women and with increasing age.
  • Although most patients with well compensated thyroid disease do not need special consideration prior to surgery, patients who have a newly diagnosed thyroid disorder around the time of surgery require a discussion of the risks and benefits of proceeding with surgery.

Preoperative management of patients  who are candidates for CABG and have:

  • Hypothyroidism
  • Hyperthyroidism

 

HYPOTHYROIDISM

Defining severity of hypothyroidism

  • Severe hypothyroidism
  • Moderate hypothyroidism
  • Mild hypothyroidism

 

 

Severe hypothyroidism

  Includes patients with:

myxedema coma

severe clinical symptoms of chronic hypothyroidism such as:

                altered mentation

                pericardial effusion

                heart failure

                very low levels of total thyroxine (T4) (eg, less than 1.0 mcg/dL) or free T4 (eg, less than 0.5        ng/dL).

  •   Weinberg AD, Brennan MD, Gorman CA, et al. Outcome of anesthesia and surgery in hypothyroid patients. Arch Intern          Med 1983; 143:893.
  •   Bennett-Guerrero E, Kramer DC, Schwinn DA. Effect of chronic and acute thyroid hormone reduction on perioperative outcome. Anesth Analg 1997; 85:30.